Updated Guidance on the Application of the CLP Criteria

The Guidance on the Application of the CLP Criteria for Part  3 Health Hazards, relating to specific concentration limits (SCLs) for four hazard classes, has been updated to provide guidance to manufacturers, importers and downstream users on how to set SCLs. The SCL concept allows fine-tuning of the contribution of certain hazardous substances to the classification of mixtures based on the potency of the substances. The updated guidance provides:

Guidance on the setting of lower and higher SCLs for substances classified for the following four health hazard classes: skin corrosion/irritation, serious eye damage/eye irritation, reproductive toxicity and specific target organ toxicity – single exposure (STOT-SE), in accordance with CLP Article 10(7);

Relevant background information on setting SCLs for the reproductive toxicity hazard class based on potency considerations included in the new Annex "Annex VI: Background document to the guidance for setting specific concentration limits for substances classified for reproductive toxicity according to Regulation (EC) No 1272/2008".