Section three for physicochemical endpoints of the Practical Guide was modified to reflect the updated sub-chapter R.7.1 Physicochemical properties within the Guidance on information requirements and chemical safety assessment R.7a: Endpoint specific guidance.
Sections four and five for the environmental and human health endpoints of the Practical Guide were updated with new and revised OECD Test Guidelines (TG), e.g. OECD TG 305 Bioaccumulation in Fish: Aqueous and Dietary Exposure, OECD TG 443 Extended One-Generation Reproductive Toxicity Study and OECD TG 405 Acute Eye Irritation/Corrosion.